Distant Intradural Metastasis by Direct Seeding Through Dural Opening From the Metastasis of Rectal Cancer / 대한척추외과학회지

Few cases of intradural metastasis of a non-neurogenic origin, without antecedent cerebral metastasis, have been reported. To the best of our knowledge; however, this is the first reported case of distant tumor metastasis via seeding to the intradural space through a dural opening, which formed a tumor mass without antecedent brain metastasis at a different spine level. The medical records and imaging studies of a 67-year-old woman suffering from lower back pain and paresis of the lower extremities, were reviewed. She had previously had rectal cancer. A decompressive laminectomy and excision of the intradural mass were performed. The histopathology study confirmed her original diagnosis.

Anterior Decompression and Fusion with Instrumentation in Osteoporotic Vertebral Fracture / 대한척추외과학회지

STUDY DESIGN: A Retrospective study OBJECTIVE: To evaluate the results after an anterior decompression and fusion, with anterior instrumentation, using a Z-plate in osteoporotic vertebral fractures. SUMMARY OF LITERATURE REVIEW: Despite conservative treatment, continuous severe pain, progressive neurological impairments and deformity may need surgical treatment in osteoporotic vertebral fractures accompanied with neurological deficit. MATERIALS AND METHODS: Fourteen patients that had undergone anterior decompression and an autogenous iliac bone graft, with anterior internal fixation, between 1997 and 2001, under the diagnosis of an osteoporotic vertebral fracture, were reviewed. The chief complaints, severity of pain measured, using the Denis pain scale, fracture patterns, fracture level, changes of kyphotic angle (revised with sagittal index) and complications were analyzed. RESULTS: Symptoms subsided completely in 5 patients, one case showed no definite improvement and 8 showed improved symptoms. The fracture levels included: 1 and 2 cases at the 11th and 12th thoracic spine, and 8, 1 and 2 in the 1st, 2nd and 3rd lumbar spine, respectively. 10 patients showed wedge type fractures, three a compression type and one a biconcave type. The average kyphotic deformity decreased 49.0% (50.9% when revised with sagittal index) after surgery, but the average loss of correction angle was 28.8% (26.0% when revised with sagittal index), compared with the immediate postoperative correction angle. THE COMPLICATIONS INCLUDED: screw loosening and adjacent vertebral fractures in 3 and 4 patients, respectively. Two patients had the combined problem of screw loosening and an adjacent vertebral fracture. CONCLUSION: In anterior decompression and fusion, with instrumentation, for osteoporotic vertebral fracture treatment, the complications were primarily related, directly or indirectly, to the underlying osteoporosis. Complete neurological recovery occurred 9 of the 11 patients, but residual pain was common.

Intertransverse Lumbar Fusion Using Calcium Sulfate as a Bone Graft Substitute in Rabbits / 대한척추외과학회지

STUDY DESIGN: Intertransverse lumbar fusion segments were evaluated in rabbits at 4, 8, 12, and 16 weeks after surgery. The calcium sulfate was used as a bone graft substitute and its fusion rate compared with the fusion rate of autogenous bone graft. OBJECTIVE: To investigate the efficacy of calcium sulfate as a bone graft substitute in achieving intertransverse fusion in rabbits. SUMMARY OF BACKGROUND: Calcium sulfate is a bone graft substitute made from medical grade calcium sulfate hemihydrate. Preclinical testing and clinical case studies demonstrate the excellent bone healing response and biocompatibility in long bone defect. MATERIALS AND METHODS: Forty adult New Zealand white rabbits were included in our study. In group I, the 0.8g of the calcium sulfate was grafted on the left inter transverse of L4-5 or L5-6 and the 0.8g of the autogenous iliac bone on the right side at the same level. In group II, the 0.4g of the calcium sulfate mixed with 0.4g of the autogenous graft on the left intertransverse of L4-5 or L5-6 and 0.8g of the autogenous iliac bone on the right side at the same level was grafted. At postoperative 4, 8, 12, 16 weeks, the plain roentgenogram was checked to evaluate the bony union. At 16 weeks, all rabbits were sacrificed and the histologic evidences of the bony union using H&E and trichrome stain were investigated. The molecular-biological study to detect the RNA of TNF-alpha was investigated in nonunion. RESULTS: Bone graft using calcium sulfate resulted in nonunion radiologically and histologically in all rabbits. 92.5% of calcium sulfate in group I and 80.0% in group II was resorbed within postoperative 12 weeks. There was statistical significance between group I and group II. In contrast, graft using autogenous cancellous bone showed complete bony union in 11 out of 20 rabbits. With molecular-biological study using PCR, the RNA of TNF-alpha was not detected from bony union site, but detected from nonunion site. CONCLUSION: The results of this study indicate that calcium sulfate is not an effective bone graft substitute for achieving stable intertransverse spinal fusion. TNF-alpha may have direct effects on autogenous graft bone with calcium sulfate resorption

The Effect of Load Sharing Wiring on the Fixation of Transverse Fracture of Porcine Patella / 대한정형외과연구학회지

Among many kinds of internal fixation techniques for the transverse fracture of the patella, AO modified tension band wiring technique and Pyrford technique have been widely used. However, it seems that those techniques are not strong enough to withstand immediate full weight bearing and full range of motion exercise postoperatively. Instead, a load sharing wiring technique seems to be more effective fixation technique. A comparative study was performed to evaluate the load sharing wiring technique using porcine patellae. Transverse fractures of thirty knees were made and were fixed with 3 different fixation technique. 1) AO modified tension band wiring technique, 2) Pyrford technique, and 3) Load sharing wiring technique. Then, those knees were mounted on the material testing system (Instron 4204(R)) and longitudinal traction was applied. The result showed that the separation of the fracture fragments was much less with the load sharing wiring technique than with the AO modified tension band wiring technique and the Pyrford tehchnique when 5 kg to 25 kg of traction was applied(P<0.05). The load sharing wiring technique showed less than 0.4mm of separation at 25~50kg of traction, where other techniques led specimen to failure. From this study, it was suggested that the load sharing wiring technique was proved to be more effective fixation technique compared to other techniques.